Æon Flux is a 2005 American science fiction spy action film directed by Karyn Kusama. The film is a loose adaptation of the animated science fiction television series of the same name, which was created by animator Peter Chung. It stars Charlize Theron as the title character. In 2011, a deadly pathogenic virus has killed 99% of the Earth's population, forcing the survivors to regroup and scatter across the Earth. 404 years later, in late 2415, all of the survivors inhabit Bregna, a walled futuristic city-state, which is ruled by a congress of scientists. Although Bregna is largely an idyllic place in the destroyed Earth, people routinely disappear and the population suffers from bad dreams. A skilled warrior, named Æon Flux, is a member of the Monicans, an underground rebel organization who communicate through telepathy-enabling technology and are led by the Handler.