Scream and Scream Again is a 1970 conspiracy-thriller / science fiction film. It marks the second teaming, after The Oblong Box, of actors Vincent Price and Christopher Lee with director Gordon Hessler. Price and Lee only share a brief scene in the film's climax, however. The movie's title, and association with stars Price, Lee and Peter Cushing have given it an undeserved reputation as a violent horror film, but the violence in the film is mostly understated and/or off-screen, while the plot owes more to films like Invasion of the Body Snatchers or 1970's era 'conspiracy thrillers' like The Parallax View. The Overlook Film Guide: Science-Fiction, acknowledges it as: "one of the best science-fiction films made in Britain." The movie's structure is fragmented, as it alternates between three distinguishable plot threads. A man jogging through suburban London grabs his heart, and collapses. He wakes up in a hospital bed. The nurse tending him give him water. She leaves. He pulls down the bed covers to discover both his legs have been amputated. He screams.