Insanitarium is a 2008 psychological horror film starring Jesse Metcalfe, Kiele Sanchez, Kevin Sussman, Olivia Munn, Carla Gallo and Peter Stormare. The film is directed by Jeff Buhler. The film follows a man, Jack (Jesse Metcalfe), faking insanity in order to save his sister, Lily (Kiele Sanchez), who has been involuntarily institutionalized. The siblings soon find that the strange doctor at the asylum, Mr. Gianetti (Peter Stormare), has been testing an experimental compound, orphium, on the patients that seems to be turning them into flesh-eating zombies; Loomis (Kurt Caceres), another patient, spreads the infection. The two siblings band together with a terminally paranoid man, Dave (Kevin Sussman), and a helpful nurse, Nancy (Olivia Munn), in the hopes of finding a way out of the asylum.