Ironweed is a 1987 American drama film directed by Héctor Babenco. It is based on the Pulitzer Prize-winning homonymous novel by William Kennedy, who also wrote the screenplay. It stars Jack Nicholson and Meryl Streep, with Carroll Baker, Michael O'Keefe, Diane Venora, Fred Gwynne, Nathan Lane, and Tom Waits in supporting roles. The story concerns the relationship of a homeless couple: Francis, an alcoholic, and Helen, a terminally ill woman during the Great Depression. Major portions of the film were shot on location in Albany, New York, including Jay Street at Lark Street, Albany Rural Cemetery and the Miss Albany Diner on North Broadway. The film was nominated for Academy Awards for Best Actor in a Leading Role (Nicholson) and Best Actress in a Leading Role (Streep).